What is qSOFA?
qSOFA (quick Sequential Organ Failure Assessment) is a simplified, three-variable bedside tool introduced as part of the Sepsis-3 consensus definitions, published by Singer and colleagues in JAMA in 2016. Unlike the full SOFA score, it requires no laboratory results, making it usable for rapid screening on general wards or in resource-limited settings, outside the ICU where SOFA was originally validated.
How to calculate qSOFA
Three criteria, each worth one point:
- Respiratory rate ≥22 breaths/min
- Altered mentation (GCS <15)
- Systolic blood pressure ≤100 mmHg
Interpretation
A score of 2 or more is associated with a substantially increased risk of poor outcome in patients with suspected infection. It should prompt further assessment - lactate, blood cultures, a full SOFA score, and consideration of early antibiotics and fluids - not be used as a final diagnostic answer on its own.
Limitations
qSOFA has lower sensitivity than SIRS criteria for detecting sepsis early, and several major guidelines (including the Surviving Sepsis Campaign) caution against using it as a sole or primary screening tool. It's best thought of as one input among several in the overall clinical assessment.
References
Singer M, Deutschman CS, Seymour CW, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016.
See also: Shock Types Explained and the Common Antibiotics Guide.